Recombinant humaan BAFF-eiwit met N-terminaal humaan Fc

Expression Host : HEK293 The protein has a predicted molecular mass of 43.2 kDa after removal of the signal peptide.The apparent molecular mass of BAFF-hFc is approximately 50-55 kDa due to glycosylation. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

TNFSF13B, BAFF, BLYS, CD257, DTL, TALL1, THANK, TNFSF20, ZTNF4, TALL-1

Q9Y275

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Delivery in 1-2 weeks

Store at -80°C for 12 months (Avoid repeated freezing and thawing)

HFc (Glu99-Ala330) BAFF (Ala134-Leu285)