Recombinant humaan BAG1-eiwit

BCL2-associated athanogene, also known as BAG1, is a member of the Bcl-2 family of proteins that play varied stimulatory or inhibitory roles in the regulation of programmed cell death. This functions in conjunction with Bcl-2 to inhibit apoptosis. Also, BAG1 has been implicated in age related neurodegenerative diseases as Alzheimer's. It is localized to the cytosol, nucleus or both. Recombinant human BAG1 was expressed in E. coli and purified by using conventional chromatography techniques.

BAG cochaperone 1, BCL2 associated athanogene, BCL2 associated athanogene 1, HAP, RAP46

E.coli

Human

Non-Tagged

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

25.9 kDa (230aa) confirmed by MALDI-TOF

BAG1, BCL2-associated athanogene 1, HAP, RAP46, BCL2-associated athanogene 1 Bag 1, BAG family molecular chaperone regulator 1, BCL 2 associated athanogene, BCL 2 Associated Athanogene 1, BCL 2 binding athanogene 1, BCL2 associated athanogene, BCL2 associated athanogene 1, Glucocorticoid receptor-associated protein RAP46, HAP1, Haptoglobin, RAP 46., ATGP0508-10 µg, ATGP0508-20 µg, ATGP0508-50 µg, ATGP0508-100 µg, ATGP0508-250 µg, ATGP0508-500 µg, ATGP0508-1 mg, ATGP0508-10, ATGP0508-20, ATGP0508-50, ATGP0508-100, ATGP0508-250, ATGP0508-500, ATGP0508-1

Wang HG., et al. (1996) Proc Natl Acad Sci u S A. 93 (14) :7063-8. ; ; Takayama S., et al. (1995) Cell. 80 (2) :279-84.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 100 mM NaCl, 10% glycerol

Apoptosis

NP_001165886

Q99933

Human

MNRSQEVTRD EESTRSEEVT REEMAAAGLT VTVTHSNEKH DLHVTSQQGS SEPVVQDLAQ VVEEVIGVPQ SFQKLIFKGK SLKEMETPLS ALGIQDGCRV MLIGKKNSPQ EEVELKKLKH LEKSVEKIAD QLEELNKELT GIQQGFLPKD LQAEALCKLD RRVKATIEQF MKILEEIDTL ILPENFKDSR LKRKGLVKKV QAFLAECDTV EQNICQETER LQSTNFALAE