Recombinant humaan BAIAP2-eiwit

BAI1-associated protein 2, also known as BAIAP2, is a ubiquitous regulator of the actin cytoskeleton. It mediates filopodia formation under the control of Rho-family GTPases. BAIAP2 is expressed in the cytoplasm and links small membrane-bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Recombinant human BAIAP2 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

BAI1-associated protein 2, BAP2, IRSP53

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

58.4 kDa (530aa)

BAIAP2, BAI1-associated protein 2, BAP2, IRSP53, ATGP1373-10 µg, ATGP1373-20 µg, ATGP1373-50 µg, ATGP1373-100 µg, ATGP1373-250 µg, ATGP1373-500 µg, ATGP1373-1 mg, ATGP1373-10, ATGP1373-20, ATGP1373-50, ATGP1373-100, ATGP1373-250, ATGP1373-500, ATGP1373-1

Funato Y., et al. (2004) Cancer Res. 64:5237-5244.; ; Choi J., et al. (2005) J Neurosci. 25:869-879.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM MES (pH 5.0) containing , 30% glycerol, 0.2M NaCl

Cytoskeleton

AAH14020.1

Q9UQB8

Human