Recombinant humaan Bcl-w eiwit

BCL2-like protein 2, also known as BCL2L2, is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. BCL2L2 is an anti apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. It is required for normal sperm maturation. Recombinant human BCL2L2, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

BCL2-like protein 2, Apoptosis regulator Bcl-W, BCLW, BCL2-like protein 2 Apoptosis regulator BCL W, BCL 2 Like 2, Bcl 2 like 2 protein, Bcl 2L2, bcl w, Bcl2 L2, BCL2 like 2, BCL2 like 2 protein, KIAA0271.

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

20.9 kDa (192aa) confirmed by MALDI-TOF

Bcl-w, BCL2-like protein 2, Apoptosis regulator Bcl-W, BCLW, BCL2-like protein 2 Apoptosis regulator BCL W, BCL 2 Like 2, Bcl 2 like 2 protein, Bcl 2L2, bcl w, Bcl2 L2, BCL2 like 2, BCL2 like 2 protein, KIAA0271., ATGP0454-10 µg, ATGP0454-20 µg, ATGP0454-50 µg, ATGP0454-100 µg, ATGP0454-250 µg, ATGP0454-500 µg, ATGP0454-1 mg, ATGP0454-10, ATGP0454-20, ATGP0454-50, ATGP0454-100, ATGP0454-250, ATGP0454-500, ATGP0454-1

Zhu X., et al. (2004) J Neurochem. 89 (5) :1233-40. ; ; Kromer G., et al. (1997) Nature Med. 3:614. ;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 100 mM NaCl, 10% glycerol

Apoptosis

NP_004041

Q92843

Human

MGSSHHHHHH SSGLVPRGSH MATPASAPDT RALVADFVGY KLRQKGYVCG AGPGEGPAAD PLHQAMRAAG DEFETRFRRT FSDLAAQLHV TPGSAQQRFT QVSDELFQGG PNWGRLVAFF VFGAALCAES VNKEMEPLVG QVQEWMVAYL ETRLADWIHS SGGWAEFTAL YGDGALEEAR RLREGNWASV RT