Recombinant humaan BCMA-eiwit met C-terminaal humaan Fc en6Ã-Zijn tag

Expression Host : HEK293 The protein has a predicted molecular mass of 32.7 kDa after removal of the signal peptide. The apparent molecular mass of BCMA-hFc-His is approximately 40 kDa due to glycosylation. B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF) .This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK.

TNFRSF17, CD269, BCM, BCMA

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Delivery in 1-2 weeks

Store at -80°C for 12 months (Avoid repeated freezing and thawing)