Recombinant humaan BCMA/TNFRSF17-eiwit

Tumor necrosis factor receptor superfamily member 17, also known as TNFRSF17, is a member of the TNF-receptor superfamily. The open reading frame of the gene encoding TNFRSF17 predicts a 184 amino acid protein with a single transmembrane domain that has no homology with any known protein sequences. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. TNFRSF17 also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. Recombinant human TNFRSF17 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Tumor necrosis factor receptor superfamily member 17, BCM, BCMA, CD269, B-cell maturation protein, TNFRSF13A

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

14.1 kDa (130aa) confirmed by MALDI-TOF

BCMA, TNFRSF17, Tumor necrosis factor receptor superfamily member 17, BCM, BCMA, CD269, ATGP1842-10 µg, ATGP1842-20 µg, ATGP1842-50 µg, ATGP1842-100 µg, ATGP1842-250 µg, ATGP1842-500 µg, ATGP1842-1 mg, ATGP1842-10, ATGP1842-20, ATGP1842-50, ATGP1842-100, ATGP1842-250, ATGP1842-500, ATGP1842-1

Chae S C., et al. (2010) Mol Cells. 29 (1) : 21-8; ; Barone F., et al. (2009) Mucosal Immunol. 2 (6) : 495-503.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol,1mM DTT

Signal Transduction

NP_001183

Q02223

Human

RKINSEP LKDEFKNTGS GLLGMANIDL EKSRTGDEII LPRGLEYTVE ECTCEDCIKS KPKVDSDHCF PLPAMEEGAT ILVTTKTNDY CKSLPAALSA TEIEKSISAR