Recombinant humaan bèta-Sarcoglycan/SGCB-eiwit

SGCB also known as beta-sarcoglycan, is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy. Recombinant human SGCB protein, fused to His-tag at N-terminus, was expressed in E. coli.

Beta-sarcoglycan, A3b, LGMD2E, SGC, Beta-SG, 43 kDa dystrophin-associated glycoprotein, 43DAG

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

27.8 kDa (255aa)

SGCB, Beta-sarcoglycan, A3b, LGMD2E, SGC, Beta sarcoglycan, ATGP3095-10 µg, ATGP3095-20 µg, ATGP3095-50 µg, ATGP3095-100 µg, ATGP3095-250 µg, ATGP3095-500 µg, ATGP3095-1 mg, ATGP3095-010, ATGP3095-020, ATGP3095-050, ATGP3095-100, ATGP3095-250, ATGP3095-500, ATGP3095-01M

Lim L.E., et al. (1995) Nat. Genet. 11:257-265; ; Bonnemann C.G.., et al. (1996) Hum. Mol. Genet. 5:1953-1961

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Signal Transduction

NP_000223

Q16585

Human

WAVIRIG PNGCDSMEFH ESGLLRFKQV SDMGVIHPLY KSTVGGRRNE NLVITGNNQP IVFQQGTTKL SVENNKTSIT SDIGMQFFDP RTQNILFSTD YETHEFHLPS GVKSLNVQKA STERITSNAT SDLNIKVDGR AIVRGNEGVF IMGKTIEFHM GGNMELKAEN SIILNGSVMV STTRLPSSSS GDQLGSGDWV RYKLCMCADG TLFKVQVTSQ NMGCQISDNP CGNTH