Recombinant humaan BEX1-eiwit

Brain expressed, X-linked 1, also known as BEX1, is signaling adapter molecule involved in p75NTR/NGFR signaling. This protein plays a role in cell cycle progression and neuronal differentiation. This protein inhibits neuronal differentiation in response to nerve growth factor (NGF) . It may act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states. Recombinant human BEX1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Brain expressed X-linked 1, Brain expressed, X-linked 1, BEX2, HBEX2, HGR74-h

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by BCA assay)

> 80% by SDS-PAGE

17.2 kDa (148aa) confirmed by MALDI-TOF

BEX1, Brain expressed X-linked 1, Brain expressed, X-linked 1, BEX2, HBEX2, HGR74-h, ATGP2178-10 µg, ATGP2178-20 µg, ATGP2178-50 µg, ATGP2178-100 µg, ATGP2178-250 µg, ATGP2178-500 µg, ATGP2178-1 mg, ATGP2178-10, ATGP2178-20, ATGP2178-50, ATGP2178-100, ATGP2178-250, ATGP2178-500, ATGP2178-1

Yang Q.-S., et al. (2002) Biochem. Genet. 40:1-12; ; Quentmeier H., et al. (2005) Leukemia. 19:1488-1489

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol

Cancer

NP_060946

Q9HBH7

Human

MGSSHHHHHH SSGLVPRGSH MGSMESKEKR AVNSLSMENA NQENEEKEQV ANKGEPLALP LDAGEYCVPR GNRRRFRVRQ PILQYRWDMM HRLGEPQARM REENMERIGE EVRQLMEKLR EKQLSHSLRA VSTDPPHHDH HDEFCLMP