Recombinant humaan BHMT2-eiwit

BHMT2 is involved in the regulation of homocysteine metabolism. Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. BHMT2 is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Recombinant human BHMT2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

S-methylmethionine-homocysteine S-methyltransferase BHMT2 isoform 1, betaine-homocysteine S-methyltransferase 2, SMM-hcy methyltransferase

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

42.7 kDa (386aa)

BHMT2, S-methylmethionine-homocysteine S-methyltransferase BHMT2 isoform 1, S-methylmethionine-homocysteine S-methyltransferase BHMT2 isoform 1, betaine--homocysteine S-methyltransferase 2, ATGP2672-10 µg, ATGP2672-20 µg, ATGP2672-50 µg, ATGP2672-100 µg, ATGP2672-250 µg, ATGP2672-500 µg, ATGP2672-1 mg, ATGP2672-10, ATGP2672-20, ATGP2672-50, ATGP2672-100, ATGP2672-250, ATGP2672-500, ATGP2672-1

Li F., et al. (2008) Mol Genet Metab. 94 (3) : 326-35.; ; Mostowaka A., et al. (2010) Eur Oral Sci. 118 (4) : 325-32.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Metabolism

NP_060084

Q9H2M3

Human

MAPAGRP GAKKGILERL ESGEVVIGDG SFLITLEKRG YVKAGLWTPE AVIEHPDAVR QLHMEFLRAG SNVMQTFTFS ASEDNMESKW EDVNAAACDL AREVAGKGDA LVAGGICQTS IYKYQKDEAR IKKLFRQQLE VFAWKNVDFL IAEYFEHVEE AVWAVEVLKE SDRPVAVTMC IGPEGDMHDI TPGECAVRLV KAGASIVGVN CRFGPDTSLK TMELMKEGLE WAGLKAHLMV QPLGFHAPDC GKEGFVDLPE YPFGLESRVA TRWDIQKYAR EAYNLGVRYI GGCCGFEPYH IRAIAEELAP ERGFLPPASE KHGSWGSGLD MHTKPWIRAR ARREYWENLL PASGRPFCPS LSKPDF