Recombinant humaan bijlagein A8/ANXA8-eiwit

ANXA8, also known as Annexin A8, a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Where co-expressed in the same tissues, ANXA8 is often expressed at a 100-fold lower level than Annexin A5. However, ANXA8 is preferentially expressed in acute promyelocytic leukemia (APL) cells which may relate to its role in hematopoietic cell differentiation. Recombinant human ANXA8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Annexin VIII, Annexin-8, Vascular anticoagulant-beta, VAC-beta, ANX8

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

39.0 kDa (347aa) confirmed by MALDI-TOF

Annexin A8, Annexin A8, ANX8, Annexin-8, Annexin VII, Vascular anticoagulant-beta, VAC-beta, Annexin A8, ATGP0682-10 µg, ATGP0682-20 µg, ATGP0682-50 µg, ATGP0682-100 µg, ATGP0682-250 µg, ATGP0682-500 µg, ATGP0682-1 mg, ATGP0682-10, ATGP0682-20, ATGP0682-50, ATGP0682-100, ATGP0682-250, ATGP0682-500, ATGP0682-1

Movitz C., et al. (2010) J Biol Chem. 285 (19) :14338-45.; ; Torosyan Y., et al. (2010) Oncogene. 29 (17) :2457-66.;

Sakamoto N et al., Anti-annexin A4 antibody as a biomarker for desquamative interstitial pneumonia. (J Autoimmun. 2025) {https://pubmed.ncbi.nlm.nih.gov/40156961/}

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 1mM DTT, 1mM EDTA, 10% glycerol

Signal Transduction

NP_001035173

P13928

Human

MGSSHHHHHH SSGLVPRGSH MAWWKSWIEQ EGVTVKSSSH FNPDPDAETL YKAMKGIGTN EQAIIDVLTK RSNTQRQQIA KSFKAQFGKD LTETLKSELS GKFERLIVAL MYPPYRYEAK ELHDAMKGLG TKEGVIIEIL ASRTKNQLRE IMKAYEEDYG SSLEEDIQAD TSGYLERILV CLLQGSRDDV SSFVDPGLAL QDAQDLYAAG EKIRGTDEMK FITILCTRSA THLLRVFEEY EKIANKSIED SIKSETHGSL EEAMLTVVKC TQNLHSYFAE RLYYAMKGAG TRDGTLIRNI VSRSEIDLNL IKCHFKKMYG KTLSSMIMED TSGDYKNALL SLVGSDP