Recombinant humaan BIN2-eiwit

BIN2, also known as bridging integrator 2 isoform1, is a cytoplasmic protein. It contains one BAR domain and Interacts with BIN1. This protein is highly expressed in some hematopoietic tissues, including peripheral blood, thymus, colon and placenta. It Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton and also modulates membrane curvature and mediates membrane tubulation. Recombinant human BIN2 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Bridging integrator 2 isoform1, BIN2, BRAP-1

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 80% by SDS-PAGE

66.1 kDa (606aa)

BIN2, Bridging integrator 2 isoform1, BIN2, BRAP-1, ATGP3671-10 µg, ATGP3671-20 µg, ATGP3671-50 µg, ATGP3671-100 µg, ATGP3671-250 µg, ATGP3671-500 µg, ATGP3671-1 mg, ATGP3671-10, ATGP3671-20, ATGP3671-50, ATGP3671-100, ATGP3671-250, ATGP3671-500, ATGP3671-1

Sanchez-Barrena MJ., et al, (2012) PLoS One. 7:e52401.; ; Hao Y., et al, (2016) Proc Natl Acad Sci U S A. 113:10418-10423.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT, 0.1mM PMSF.

Cell Cycle

NP_057377

Q9UBW5

Human

Ala

ADPMRGMPGA RTSSSGASEN HRARGQGGGP QGVGRMAEGK AGGAAGLFAK QVQKKFSRAQ EKVLQKLGKA VETKDERFEQ SASNFYQQQA EGHKLYKDLK NFLSAVKVMH ESSKRVSETL QEIYSSEWDG HEELKAIVWN NDLLWEDYEE KLADQAVRTM EIYVAQFSEI KERIAKRGRK LVDYDSARHH LEAVQNAKKK DEAKTAKAEE EFNKAQTVFE DLNQELLEEL PILYNSRIGC YVTIFQNISN LRDVFYREMS KLNHNLYEVM SKLEKQHSNK VFVVKGLSSS SRRSLVISPP VRTATVSSPL TSPTSPSTLS LKSESESVSA TEDLAPDAAQ GEDNSEIKEL LEEEEIEKEG SEASSSEEDE PLPACNGPAQ AQPSPTTERA KSQEEVLPSS TTPSPGGALS PSGQPSSSAT EVVLRTRTAS EGSEQPKKRA SIQRTSAPPS RPPPPRATAS PRPSSGNIPS SPTASGGGSP TSPRASLGTG TASPRTSLEV SPNPEPPEKP VRTPEAKENE NIHNQNPEEL CTSPTLMTSQ VASEPGEAKK MEDKEKDNKL ISANSSEGQD QLQVSMVPEN NNLTAPEPQE EVSTSENPQL HHHHHH