Recombinant humaan BLC/BCA-1/CXCL13-eiwit

B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1) . It may therefore function in the homing of B lymphocytes to follicles. Recombinant human CXCL13 protein, fused to His-tag at N-terminus, was expressed in E. coli

ANGIE, ANGIE2, B cell-attracting chemokine 1, B lymphocyte chemoattractant, BCA1, BCA-1, BLC, BLR1L, Chemokine (C-X-C motif) ligand 13, CXC chemokine BLC, C-X-C motif chemokine 13 precursor, SCYB13, Small-inducible cytokine B13

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

12.7 kDa (110aa)

CXCL13, BLBCA1, C-X-C motif chemokine 13 precursor, Chemokine (C-X-C motif) ligand 13, ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13, ATGP2437-10 µg, ATGP2437-20 µg, ATGP2437-50 µg, ATGP2437-100 µg, ATGP2437-250 µg, ATGP2437-500 µg, ATGP2437-1 mg, ATGP2437-10, ATGP2437-20, ATGP2437-50, ATGP2437-100, ATGP2437-250, ATGP2437-500, ATGP2437-1

Gunn M.D., Ngo V.N.. et al. (1998) . Nature 391:799-803

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing , 10% glycerol, 0.4M urea

Hormones & Cytokines

NP_006410

O43927

Human

MGSSHHHHHH SSGLVPRGSH MGSVLEVYYT SLRCRCVQES SVFIPRRFID RIQILPRGNG CPRKEIIVWK KNKSIVCVDP QAEWIQRMME VLRKRSSSTL PVPVFKRKIP