Recombinant humaan BMP-3b/GDF-10 eiwit

GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Recombinant GDF10 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Growth differentiation factor 10, GDF-10, Bone morphogenetic protein 3b [Precursor], Bone inducing protein, BMP-3b, BIP

E.coli

Human

Non-Tagged

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

12.5 kDa (111aa) confirmed by MALDI-TOF

BMP3b, GDF10, Growth differentiation factor 10, BMP-3b, BMP3B, BIP, GDF-10, Growth differentiation factor 10 BMP 3b, BMP3B, Bone inducing protein, Bone morphogenetic protein 3b [Precursor], GDF 10, ATGP0336-10 µg, ATGP0336-20 µg, ATGP0336-50 µg, ATGP0336-100 µg, ATGP0336-250 µg, ATGP0336-500 µg, ATGP0336-1 mg, ATGP0336-10, ATGP0336-20, ATGP0336-50, ATGP0336-100, ATGP0336-250, ATGP0336-500, ATGP0336-1

Cunningham NS., et al. (1995) Growth Factors. 12 (2) :99-109.; ; Ducy P., et al. (2000) Kidney Int. 57 (6) :2207-14.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 10 mM Sodium Citrate buffer (pH 3.5) containing 0.1M NaCl, 1mM DTT, 40% glycerol

Hormones & Cytokines

NP_004953.1

P55107

Human

MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R