Recombinant humaan BMP-6 eiwit

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, BMP6 has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. Recombinant human BMP6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Bone morphogenetic protein 6, BMP6, VG-1-related protein, VG-1-R, VGR-1, VGR

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

18 kDa (164aa) confirmed by MALDI-TOF

BMP6, ATGP2090-10 µg, ATGP2090-20 µg, ATGP2090-50 µg, ATGP2090-100 µg, ATGP2090-250 µg, ATGP2090-500 µg, ATGP2090-1 mg, ATGP2090-10, ATGP2090-20, ATGP2090-50, ATGP2090-100, ATGP2090-250, ATGP2090-500, ATGP2090-1

Ebisawa T, Tada K, et al. (1999) . J Cell Sci. 112 (Pt 20) :3519-27.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 10 mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol

Hormones & Cytokines

NP_001709

P22004

Human

MSASSR RRQQSRNRST QSQDVARVSS ASDYNSSELK TACRKHELYV SFQDLGWQDW IIAPKGYAAN YCDGECSFPL NAHMNATNHA IVQTLVHLMN PEYVPKPCCA PTKLNAISVL YFDDNSNVIL KKYRNMVVRA CGCH