Recombinant humaan BMP-8b eiwit

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. Recombinant human BMP8B protein, fused to His-tag at N-terminus, was expressed in E. coli.

Bone morphogenetic protein 8B, BMP8, OP2, Osteogenic protein 2

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

18.1 kDa (162aa)

BMP8b, Bone morphogenetic protein 8B, BMP8, OP2, ATGP2743-10 µg, ATGP2743-20 µg, ATGP2743-50 µg, ATGP2743-100 µg, ATGP2743-250 µg, ATGP2743-500 µg, ATGP2743-1 mg, ATGP2743-10, ATGP2743-20, ATGP2743-50, ATGP2743-100, ATGP2743-250, ATGP2743-500, ATGP2743-1

Oezkaynak E., et al. (1992) J. Biol. Chem. 267:25220-25227; ; Gregory S.G., et al. (2006) Nature. 441:315-321;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Hormones & Cytokines

NP_001711

P34820

Human

MGSSHHHHHH SSGLVPRGSH MGSAVRPLRR RQPKKSNELP QANRLPGIFD DVHGSHGRQV CRRHELYVSF QDLGWLDWVI APQGYSAYYC EGECSFPLDS CMNATNHAIL QSLVHLMMPD AVPKACCAPT KLSATSVLYY DSSNNVILRK HRNMVVKACG CH