Recombinant humaan CAB39L-eiwit

Calcium-binding protein 39-like, also known as CAB39L, is similar to MO25 and is found in the serum of nearly half of all patients diagnosed with acute monocytic leukemia. This protein suggests a role for CAB39L in carcinogenesis. Also, LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the CAB39L. Recombinant human CAB39L protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Calcium-binding protein 39-like, MO25-BETA, MO2L

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

41.5 kDa (360aa) confirmed by MALDI-TOF

CAB39L, Calcium-binding protein 39-like, MO25-BETA, MO2L, ATGP1926-10 µg, ATGP1926-20 µg, ATGP1926-50 µg, ATGP1926-100 µg, ATGP1926-250 µg, ATGP1926-500 µg, ATGP1926-1 mg, ATGP1926-10, ATGP1926-20, ATGP1926-50, ATGP1926-100, ATGP1926-250, ATGP1926-500, ATGP1926-1

Boudeau J., et al. (2004) J Cell Sci. 117:6365-6375.; ; Taylor E B., et al. (2005) Am J Physiol Endocrinol Metab. 288) :E1055-1061.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Metabolism

NP_112187

Q9H9S4

Human

MKKMPLF SKSHKNPAEI VKILKDNLAI LEKQDKKTDK ASEEVSKSLQ AMKEILCGTN EKEPPTEAVA QLAQELYSSG LLVTLIADLQ LIDFEGKKDV TQIFNNILRR QIGTRSPTVE YISAHPHILF MLLKGYEAPQ IALRCGIMLR ECIRHEPLAK IILFSNQFRD FFKYVELSTF DIASDAFATF KDLLTRHKVL VADFLEQNYD TIFEDYEKLL QSENYVTKRQ SLKLLGELIL DRHNFAIMTK YISKPENLKL MMNLLRDKSP NIQFEAFHVF KVFVASPHKT QPIVEILLKN QPKLIEFLSS FQKERTDDEQ FADEKNYLIK QIRDLKKTAP