Recombinant humaan Calbindin 2/CALB2-eiwit

CALB2 is an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Recombinant human CALB2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

CR, Calretinin, CALB2, CAL2, CAB29, 29 kDa calbindin

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

33.7 kDa (291aa) confirmed by MALDI-TOF

Calretinin, CALB2, Calretinin, CALB2, CAL2, CR, 29 kDa calbindin, Calretinin, ATGP0694-10 µg, ATGP0694-20 µg, ATGP0694-50 µg, ATGP0694-100 µg, ATGP0694-250 µg, ATGP0694-500 µg, ATGP0694-1 mg, ATGP0694-10, ATGP0694-20, ATGP0694-50, ATGP0694-100, ATGP0694-250, ATGP0694-500, ATGP0694-1

Rogers J.H., et al. (1987) J. Cell Biol. 105 (3) :1343-53; ; Dreher B., et al. (1996) J. Comp. Neurol. 376 (2) :223-40;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Neuroscience

AAH15484

P22676

Human

MAGPQQQPPY LHLAELTASQ FLEIWKHFDA DGNGYIEGKE LENFFQELEK ARKGSGMMSK SDNFGEKMKE FMQKYDKNSD GKIEMAELAQ ILPTEENFLL CFRQHVGSST EFMEAWRKYD TDRSGYIEAN ELKGFLSDLL KKANRPYDEP KLQEYTQTIL RMFDLNGDGK LGLSEMSRLL PVQENFLLKF QGMKLTSEEF NAIFTFYDKD RSGYIDEHEL DALLKDLYEK NKKEMNIQQL TNYRKSVMSL AEAGKLYRKD LEIVLCSEPP M