Recombinant humaan Calbindin1-eiwit

Calbindin 1 is a calcium binding protein belonging to the troponin C superfamily. Calbindin is expressed in neural tissues. It plays an essential role in calcium regulation (including calcium transport and uptake, calcification of bone and teeth) and calcium related signalling in neurons and transiently in embryological development. This calbindin also has a role in protecting neurons from apoptotic cell death. Disregulation of this calbindin protein relates to epilepsy, amyotrophic lateral sclerosis, Huntington's disease. Recombinant human Calbindin1 was expressed in E. coli and purified by using conventional chromatography techniques.

CAB27, Calbindin D28, D-28K, CALB1, calbindin 1 28kDa, CALB, Calbindin1

E.coli

Human

Non-Tagged

SDS-PAGE

1 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

30 kDa (261aa) confirmed by MALDI-TOF

Calbindin1, CAB27, Calbindin D28, D-28K, CALB1, calbindin 1 28kDa, CALB, Calbindin1, ATGP0381-10 µg, ATGP0381-20 µg, ATGP0381-50 µg, ATGP0381-100 µg, ATGP0381-250 µg, ATGP0381-500 µg, ATGP0381-1 mg, ATGP0381-10, ATGP0381-20, ATGP0381-50, ATGP0381-100, ATGP0381-250, ATGP0381-500, ATGP0381-1

Heizmann CW., et al. (1988) J Cardiovasc Pharmacol. 5:S30-7.; ; Kaqi u., et al. (1988) Cell Tissue Res. 252 (2) :359-65. ;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 2mM EDTA

Neuroscience

NP_004920

P05937

Human

MAESHLQSSL ITASQFFEIW LHFDADGSGY LEGKELQNLI QELQQARKKA GLELSPEMKT FVDQYGQRDD GKIGIVELAH VLPTEENFLL LFRCQQLKSC EEFMKTWRKY DTDHSGFIET EELKNFLKDL LEKANKTVDD TKLAEYTDLM LKLFDSNNDG KLELTEMARL LPVQENFLLK FQGIKMCGKE FNKAFELYDQ DGNGYIDENE LDALLKDLCE KNKQDLDINN ITTYKKNIMA LSDGGKLYRT DLALILCAGD N