Recombinant humaan Calneuron 1/CALN1-eiwit

CALN1 is high similarity to the calcium-binding proteins of the calmodulin family. This protein contains two EF-hand domains and potential calcium-binding sites. Also, It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CALN1 play a role in the physiology of neurons and is potentially important in memory and learning. Recombinant human CALN1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Calcium-binding protein 8, CABP8, Calneuron-1, CaBP8, Calneuron I

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

24.0 kDa (212aa) confirmed by MALDI-TOF

CALN1, Calcium-binding protein 8, CABP8, Calneuron-1, CaBP8, Calneuron I, ATGP0772-10 µg, ATGP0772-20 µg, ATGP0772-50 µg, ATGP0772-100 µg, ATGP0772-250 µg, ATGP0772-500 µg, ATGP0772-1 mg, ATGP0772-10, ATGP0772-20, ATGP0772-50, ATGP0772-100, ATGP0772-250, ATGP0772-500, ATGP0772-1

McCue HV., et al. (2009) Biochem Biophys Res Commun. 380 (4) :825-31; ; Wu Y.-Q., et al. (2006) Mol. Genet. Metab. 72:343-350;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 50 mM NaCl, 0.1mM PMSF

Neuroscience

NP_001017440

Q9BXU9

Human

MGSSHHHHHH SSGLVPRGSH MPFHHVTAGL LYKGNYLNRS LSAGSDSEQL ANISVEELDE IREAFRVLDR DGNGFISKQE LGMAMRSLGY MPSEVELAII MQRLDMDGDG QVDFDEFMTI LGPKLVSSEG RDGFLGNTID SIFWQFDMQR ITLEELKHIL YHAFRDHLTM KDIENIIINE EESLNETSGN CQTEFEGVHS QKQNRQTCVR KS