Recombinant humaan Calreticuline-2-eiwit

Calreticulin 3, also known as CALR3, is a member of the calreticulin (CRT) family. It is calcium-binding chaperones that are localized to the endoplasmic reticulum or sarcoplasmic reticulum in eukaryotes. CALR3 assists in the calreticulin/calnexin cycle, where it is involved in protein-folding, oligomeric assembly and quality control in the ER. With specific expression in testis, CALR3 has been implicated as a cancer-testis antigen due to its frequent expression in various cancers. Recombinant human CALR3 protein was expressed in E. coli.

Calreticulin 3, CRT2, FLJ25355, MGC26577

E.coli

Human

Non-Tagged

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

43 kDa (366aa)

Calreticulin2, Calreticulin 3, CRT2, FLJ25355, MGC26577, ATGP2573-10 µg, ATGP2573-20 µg, ATGP2573-50 µg, ATGP2573-100 µg, ATGP2573-250 µg, ATGP2573-500 µg, ATGP2573-1 mg, ATGP2573-10, ATGP2573-20, ATGP2573-50, ATGP2573-100, ATGP2573-250, ATGP2573-500, ATGP2573-1

Persson S., et al. (2002) Gene. 297: 151-158.; ; Michalak M., et al. (1998) Biochem Cell Biol. 76: 779-785.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Signal Transduction

NP_659483

Q96L12

Human

MTVYFQEEFL DGEHWRNRWL QSTNDSRFGH FRLSSGKFYG HKEKDKGLQT TQNGRFYAIS ARFKPFSNKG KTLVIQYTVK HEQKMDCGGG YIKVFPADID QKNLNGKSQY YIMFGPDICG FDIKKVHVIL HFKNKYHENK KLIRCKVDGF THLYTLILRP DLSYDVKIDG QSIESGSIEY DWNLTSLKKE TSPAESKDWE QTKDNKAQDW EKHFLDASTS KQSDWNGDLD GDWPAPMLQK PPYQDGLKPE GIHKDVWLHR KMKNTDYLTQ YDLSEFENIG AIGLELWQVR SGTIFDNFLI TDDEEYADNF GKATWGETKG PEREMDAIQA KEEMKKAREE EEEELLSGKI NRHEHYFNQF HRRNEL