Recombinant humaan Caseïnekinase 1 alfa/CSNK1A1-eiwit

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. CSNK1A1 participates in Wnt signaling and phosphorylates CTNNB1 at 'Ser-45'. It may play a role in segregating chromosomes during mitosis. Recombinant human CSNK1a1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Casein kinase 1 alpha 1, CK1, CK1a, CK1alpha, CKIa, CKIalpha, Clock regulator kinase

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

41 kDa (357aa)

CSNK1A1, Casein kinase 1 alpha 1, Casein kinase 1, alpha 1, CK1, HLCDGP1, PRO2975, ATGP2610-10 µg, ATGP2610-20 µg, ATGP2610-50 µg, ATGP2610-100 µg, ATGP2610-250 µg, ATGP2610-500 µg, ATGP2610-1 mg, ATGP2610-10, ATGP2610-20, ATGP2610-50, ATGP2610-100, ATGP2610-250, ATGP2610-500, ATGP2610-1

Dubois T, Kerai P, et al. (2001) . J Biol Chem. 276 (22) :18757-64.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Stem cell

NP_001883

P48729

Human

MGSSHHHHHH SSGLVPRGSH MASSSGSKAE FIVGGKYKLV RKIGSGSFGD IYLAINITNG EEVAVKLESQ KARHPQLLYE SKLYKILQGG VGIPHIRWYG QEKDYNVLVM DLLGPSLEDL FNFCSRRFTM KTVLMLADQM ISRIEYVHTK NFIHRDIKPD NFLMGIGRHC NKLFLIDFGL AKKYRDNRTR QHIPYREDKN LTGTARYASI NAHLGIEQSR RDDMESLGYV LMYFNRTSLP WQGLKAATKK QKYEKISEKK MSTPVEVLCK GFPAEFAMYL NYCRGLRFEE APDYMYLRQL FRILFRTLNH QYDYTFDWTM LKQKAAQQAA SSSGQGQQAQ TPTGKQTDKT KSNMKGF