Recombinant humaan Cathepsine W-eiwit

The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. Recombinant human CTSW protein, fused to His-tag at N-terminus, was expressed in E. coli.

Cathepsin W preproprotein, CTSW, CatW, Lymphopain

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

42 kDa (378aa)

CTSW, Cathepsin W preproprotein, ATGP2501-10 µg, ATGP2501-20 µg, ATGP2501-50 µg, ATGP2501-100 µg, ATGP2501-250 µg, ATGP2501-500 µg, ATGP2501-1 mg, ATGP2501-10, ATGP2501-20, ATGP2501-50, ATGP2501-100, ATGP2501-250, ATGP2501-500, ATGP2501-1

Raab AK, Monkemuller K, et al. (2011) . Biol Chem. 392 (12) :1167-72. ; ; Stoeckle C, Gouttefangeas C, et al. (2009) . Exp Hematol. 37 (2) :266-75.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Immunology

NP_001326

P56202

Human

IRGPLRA QDLGPQPLEL KEAFKLFQIQ FNRSYLSPEE HAHRLDIFAH NLAQAQRLQE EDLGTAEFGV TPFSDLTEEE FGQLYGYRRA AGGVPSMGRE IRSEEPEESV PFSCDWRKVA GAISPIKDQK NCNCCWAMAA AGNIETLWRI SFWDFVDVSV QELLDCGRCG DGCHGGFVWD AFITVLNNSG LASEKDYPFQ GKVRAHRCHP KKYQKVAWIQ DFIMLQNNEH RIAQYLATYG PITVTINMKP LQLYRKGVIK ATPTTCDPQL VDHSVLLVGF GSVKSEEGIW AETVSSQSQP QPPHPTPYWI LKNSWGAQWG EKGYFRLHRG SNTCGITKFP LTARVQKPDM KPRVSCPP