Recombinant humaan Cathepsine Z-eiwit

CTSZ is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. At least two transcript variants of this gene have been found, but the full-length nature of only one of them has been determined. Recombinant human CTSZ protein, fused to His-tag at N-terminus, was expressed in E. coli.

Carboxypeptidase LB, Cathepsin B2, Cathepsin IV, Cathepsin P, Cathepsin X, Cathepsin Y, Cathepsin Z, Cathepsin Z preproprotein, Cathepsin Z1, CatX, CTSP, CTSX, CTSZ, Cysteine-type carboxypeptidase, Lysosomal carboxypeptidase B

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

29.5 kDa (265aa)

Carboxypeptidase LB, Cathepsin B2, Cathepsin IV, Cathepsin P, Cathepsin X, Cathepsin X Z P, Cathepsin X, Z, P, Cathepsin X/Z/P, Cathepsin XZP, Cathepsin Y, Cathepsin Z, Cathepsin Z preproprotein, Cathepsin Z1, Cathepsin-IV, Cathepsin-X, Cathepsin-Y, Cathepsin-Z, Cathepsin-Z1, Cathepsin-B2, CatX, CTSP, CTSX, CTSZ, Cysteine-type carboxypeptidase, Lysosomal carboxypeptidase B, ATGP2328-10 µg, ATGP2328-20 µg, ATGP2328-50 µg, ATGP2328-100 µg, ATGP2328-250 µg, ATGP2328-500 µg, ATGP2328-1 mg, ATGP2328-010, ATGP2328-020, ATGP2328-050, ATGP2328-100, ATGP2328-250, ATGP2328-500, ATGP2328-01M

Santamaria I, . et al. (1998) . J Biol Chem 273 (27) : 16816-23.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Cancer

NP_001327

Q9UBR2

Human

LPKSWDW RNVDGVNYAS ITRNQHIPQY CGSCWAHAST SAMADRINIK RKGAWPSTLL SVQNVIDCGN AGSCEGGNDL SVWDYAHQHG IPDETCNNYQ AKDQECDKFN QCGTCNEFKE CHAIRNYTLW RVGDYGSLSG REKMMAEIYA NGPISCGIMA TERLANYTGG IYAEYQDTTY INHVVSVAGW GISDGTEYWI VRNSWGEPWG ERGWLRIVTS TYKDGKGARY NLAIEEHCTF GDPIV