Recombinant humaan CCL11/Eotaxine-1-eiwit

CCL11 is a small cytokine belonging to the CC chemokine family that is also known as eotaxin-1. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2, CCR3 and CCR5. Recombinant CCL11 protein was expressed in E. coli and purified by using conventional chromatography techniques

Small inducible cytokine A11, SCYA11, Small inducible cytokine A11 CCL 11, Chemokine C C motif ligand 11, Chemokine CC Motif Ligand 11, Chemokine ligand 11, Eosinophil Chemotactic Protein, MGC22554, SCYA 11, Small inducible cytokine subfamily A (Cys Cys) member 11, Small inducible cytokine subfamily A member 11.

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

10.6 kDa (95aa) confirmed by MALDI-TOF

CCL11, Eotaxin, Small inducible cytokine A11, SCYA11, Small inducible cytokine A11 CCL 11, Chemokine C C motif ligand 11, Chemokine CC Motif Ligand 11, Chemokine ligand 11, Eosinophil Chemotactic Protein, MGC22554, SCYA 11, Small inducible cytokine subfamily A (Cys Cys) member 11, Small inducible cytokine subfamily A member 11., ATGP0447-10 µg, ATGP0447-20 µg, ATGP0447-50 µg, ATGP0447-100 µg, ATGP0447-250 µg, ATGP0447-500 µg, ATGP0447-1 mg, ATGP0447-10, ATGP0447-20, ATGP0447-50, ATGP0447-100, ATGP0447-250, ATGP0447-500, ATGP0447-1

Imai T., et al. (1996) J Biol Chem. 271 (35) : 21514-21; ; Kakinuma T, ., et al. (2002) Cytokine. 20 (1) :1-6.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.

Hormones & Cytokines

NP_002977

P51671

Human

MGPASVPTTC CFNLANRKIP LQRLESYRRI TSGKCPQKAV IFKTKLAKDI CADPKKKWVQ DSMKYLDQKS PTPKP