Recombinant humaan CCL17/TARC-eiwit

CCL17 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC) . This protein is involved in immunoregulatory and inflammatory processes. It is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL17 was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Chemokine (C-C motif) ligand 17, A-152E5.3, ABCD-2, SCYA17, TARC, Chemokine (C-C motif) ligand 17 A152E53, ABCD2, CC Chemokine TARC, CCL17, Chemokine CC Motif Ligand 17, MGC138271, MGC138273, Small Inducible Cytokine A17, Small Inducible Cytokine A17 Precursor, Small Inducible Cytokine Subfamily A (Cys Cys), Small Inducible Cytokine Subfamily A (Cys Cys) Member 17, T Cell Directed CC Chemokine, Thymus and activation regulated chemokine

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

10.3 kDa (92aa) confirmed by MALDI-TOF

CCL17, TARC, Chemokine (C-C motif) ligand 17, A-152E5.3, ABCD-2, SCYA17, TARC, Chemokine (C-C motif) ligand 17 A152E53, ABCD2, CC Chemokine TARC, CCL17, Chemokine CC Motif Ligand 17, MGC138271, MGC138273, Small Inducible Cytokine A17, Small Inducible Cytokine A17 Precursor, Small Inducible Cytokine Subfamily A (Cys Cys), Small Inducible Cytokine Subfamily A (Cys Cys) Member 17, T Cell Directed CC Chemokine, Thymus and activation regulated chemokine, ATGP0367-10 µg, ATGP0367-20 µg, ATGP0367-50 µg, ATGP0367-100 µg, ATGP0367-250 µg, ATGP0367-500 µg, ATGP0367-1 mg, ATGP0367-10, ATGP0367-20, ATGP0367-50, ATGP0367-100, ATGP0367-250, ATGP0367-500, ATGP0367-1

Imai T., et al. (1996) J Biol Chem. 271 (35) : 21514-21.; ; Kakinuma T., et al. (2002) Cytokine. (1) :1-6.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_002978

Q92583

Human

MGSSHHHHHH SSGLVPRGSH MARGTNVGRE CCLEYFKGAI PLRKLKTWYQ TSEDCSRDAI VFVTVQGRAI CSDPNNKRVK NAVKYLQSLE RS