Recombinant humaan CCL18/MIP-4 eiwit

CCL18, also known as chemokine (C-C motif) ligand 18, a chemotactic factor that attracts lymphocytes but not monocytes or granulocytes may be involved in B cell migration into B cell follicles in lymph nodes. It attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T cells, CD4+ and CD8+ T cells and thus may play a role in both humoral and cell-mediated immunity responses. Recombinant human CCL18 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

C-C motif chemokine ligand 18, Alternative macrophage activation-associated CC chemokine 1, AMAC-1, CC chemokine PARC, Dendritic cell chemokine 1, DC-CK1, Macrophage inflammatory protein 4, MIP-4, Pulmonary and activation-regulated chemokine, PARC, Small-inducible cytokine A18, SCYA18

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by BCA assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

10.4 kDa (93aa) confirmed by MALDI-TOF

CCL18, PARC, C-C motif chemokine 18, AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18, ATGP0853-10 µg, ATGP0853-20 µg, ATGP0853-50 µg, ATGP0853-100 µg, ATGP0853-250 µg, ATGP0853-500 µg, ATGP0853-1 mg, ATGP0853-10, ATGP0853-20, ATGP0853-50, ATGP0853-100, ATGP0853-250, ATGP0853-500, ATGP0853-1

Lukina E., et al. (2010) Blood. 116 (6) :893-9. ; ; Kato A., et al. (2009) J Immunol. 182 (11) :7233-43.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 10 mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol

Hormones & Cytokines

NP_002979

P55774

Human

MGSSHHHHHH SSGLVPRGSH MGSHMQVGTN KELCCLVYTS WQIPQKFIVD YSETSPQCPK PGVILLTKRG RQICADPNKK WVQKYISDLK LNA