Recombinant humaan CCL19/MIP-3 bèta-eiwit

CCL19 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC) . This protein is involved in immunoregulatory and inflammatory processes. It elicits its effects on its target cells by binding to the chemokine receptor chemokine receptor CCR7. It attracts certain cells of the immune system, including dendritic cells and antigen-engaged B cells, CCR7+ effector-memory T-Cells. Recombinant human CCL19 protein, fused to T7-tag at N-terminus, was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

C-C motif chemokine ligand 19, Beta-chemokine exodus-3, CK beta-11, Epstein-Barr virus-induced molecule 1 ligand chemokine, EBI1 ligand chemokine, ELC, Macrophage inflammatory protein 3 beta, MIP-3-beta, MIP3B, Small-inducible cytokine A19, SCYA19, Beta chemokine exodus-3, Exodus-3, CKb11

E.coli

Human

T7-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

10.4 kDa (93aa) confirmed by MALDI-TOF

CCL19, MIP3 b, C-C motif chemokine 19, CKb11, ELC, MIP-3b, MIP3B, SCYA19, C-C motif chemokine 19 Beta chemokine exodus 3, C C chemokine ligand 19, CC chemokine ligand 19, CCL19, Chemokine (C C motif) ligand 19, Chemokine (CC motif) ligand 19, Chemokine CC Motif Ligand 19, CK beta 11, EBI1 ligand chemokine, Exodus 3, MGC34433, MIP 3 beta, MIP3 beta, OTTHuMP00000000531, Small inducible cytokine A19, ATGP0580-10 µg, ATGP0580-20 µg, ATGP0580-50 µg, ATGP0580-100 µg, ATGP0580-250 µg, ATGP0580-500 µg, ATGP0580-1 mg, ATGP0580-10, ATGP0580-20, ATGP0580-50, ATGP0580-100, ATGP0580-250, ATGP0580-500, ATGP0580-1

Yoshida R, et al. (1997) J Biol Chem. 272 (21) :13803-9.; ; Robbiani DF, et al. (2000) Cell. 103 (5) :757-68.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_006265.1

Q99731

Human

GTND AEDCCLSVTQ KPIPGYIVRN FHYLLIKDGC RVPAVVFTTL RGRQLCAPPD QPWVERIIQR LQRTSAKMKR RSS