Recombinant humaan CCL22/MDC-eiwit

CCL22/MDC is a small cytokine belonging to the CC chemokine family. This protien displays chemotactic activity for natural killer cells, chronically activated T lymphocytes, monocytes and dendritic cells. It interacts with cell surface chemokine receptors CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. Recombinant human CCL22/MDC, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

C-C motif chemokine ligand 22, CC chemokine STCP-1, MDC 1-69, Macrophage-derived chemokine, MDC, Small-inducible cytokine A22, SCYA22, Stimulated T-cell chemotactic protein 1, ABCD-1, DC/B-CK, A-152E5.1

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

10.3 kDa (90aa) confirmed by MALDI-TOF

CCL22, MDC, Chemokine (C-C motif) ligand 22 / Macrophage-Derived Chemokine, SCYA22, STCP-1, Chemokine (C-C motif) ligand 22 / Macrophage-Derived Chemokine DC/B CK, A 152E5.1, ABCD 1, ABCD1, CC chemokine STCP 1, ccl 22, CCL22, MGC34554, Small inducible cytokine subfamily A (Cys Cys) member 22, STCP 1, STCP1, Stimulated T cell chemotactic protein 1, ATGP0397-10 µg, ATGP0397-20 µg, ATGP0397-50 µg, ATGP0397-100 µg, ATGP0397-250 µg, ATGP0397-500 µg, ATGP0397-1 mg, ATGP0397-10, ATGP0397-20, ATGP0397-50, ATGP0397-100, ATGP0397-250, ATGP0397-500, ATGP0397-1

Wang G., et al. (2009) . Cancer. 115 (11) :2430-7; ; Silvano Sozzani., et al. (2000) . Journal of Leukocyte Biology. 68:400-404;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_002981

O00626

Human

MGSSHHHHHH SSGLVPRGSH MGPYGANMED SVCCRDYVRY RLPLRVVKHF YWTSDSCPRP GVVLLTFRDK EICADPRVPW VKMILNKLSQ