Recombinant humaan CCL26/Eotaxine-3-eiwit

CCL26 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC) . This protein is involved in immunoregulatory and inflammatory processes. It is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26 was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

C-C motif chemokine ligand 26, CC chemokine IMAC, Eotaxin-3, Macrophage inflammatory protein 4-alpha, MIP-4-alpha, MIP-4a, Small-inducible cytokine A26, SCYA26, Thymic stroma chemokine-1, TSC-1, Chemokine N1

E.coli

Human

Non-Tagged

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

8.5 kDa (72aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

CCL26, Eotaxin3, Chemokine (C-C motif) ligand 26, Eotaxin-3, IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1, Chemokine (C-C motif) ligand 26 CCL 26, CCL26, Chemokine (C C motif) ligand 26, macrophage inflammatory protein 4-alpha, MIP 4a, MIP 4alpha, MIP4a, MIP4alpha, SCYA 26, Small inducible cytokine A26, Small inducible cytokine subfamily A (Cys Cys) member 26, Small inducible cytokine subfamily A member 26, Thymic stroma chemokine 1, TSC 1, TSC1, ATGP0378-10 µg, ATGP0378-20 µg, ATGP0378-50 µg, ATGP0378-100 µg, ATGP0378-250 µg, ATGP0378-500 µg, ATGP0378-1 mg, ATGP0378-10, ATGP0378-20, ATGP0378-50, ATGP0378-100, ATGP0378-250, ATGP0378-500, ATGP0378-1

Imai T., et al. (1996) J Biol Chem. 271 (35) : 21514-21.; ; Kakinuma T, . et al. (2002) Cytokine. 20 (1) :1-6.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_006063

Q9Y258

Human

MTRGSDISKT CCFQYSHKPL PWTWVRSYEF TSNSCSQRAV IFTTKRGKKV CTHPRKKWVQ KYISLLKTPK QL