Recombinant humaan CCNI-eiwit

CCNI belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined. Recombinant human CCNI protein, fused to His-tag at N-terminus, was expressed in E. coli

Cyclin-I, CYC1, CYI

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

44.9 kDa (400aa)

CCNI, Cyclin-I, CYC1, CYI, ATGP2277-10 µg, ATGP2277-20 µg, ATGP2277-50 µg, ATGP2277-100 µg, ATGP2277-250 µg, ATGP2277-500 µg, ATGP2277-1 mg, ATGP2277-10, ATGP2277-20, ATGP2277-50, ATGP2277-100, ATGP2277-250, ATGP2277-500, ATGP2277-1

Nakamura T.., et al. (1995) . Exp. Cell Res. 221:534-542

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Signal Transduction

NP_006826

Q14094

Human

MKFPGPL ENQRLSFLLE KAITREAQMW KVNVRKMPSN QNVSPSQRDE VIQWLAKLKY QFNLYPETFA LASSLLDRFL ATVKAHPKYL SCIAISCFFL AAKTVEEDER IPVLKVLARD SFCGCSSSEI LRMERIILDK LNWDLHTATP LDFLHIFHAI AVSTRPQLLF SLPKLSPSQH LAVLTKQLLH CMACNQLLQF RGSMLALAMV SLEMEKLIPD WLSLTIELLQ KAQMDSSQLI HCRELVAHHL STLQSSLPLN SVYVYRPLKH TLVTCDKGVF RLHPSSVPGP DFSKDNSKPE VPVRGTAAFY HHLPAASGCK QTSTKRKVEE MEVDDFYDGI KRLYNEDNVS ENVGSVCGTD LSRQEGHASP CPPLQPVSVM