Recombinant humaan CD-M6PR eiwit

M6PR is a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. This protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. Recombinant human M6PR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques..

Cation-dependent mannose-6-phosphate receptor isoform 1, CD-MPR, MPR 46, MPR-46, MPR46, SMPR

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

20.3 kDa (182aa) confirmed by MALDI-TOF

CD-M6PR, Cation-dependent mannose-6-phosphate receptor isoform 1, CD-MPR, MPR 46, MPR-46, MPR46, SMPR, ATGP2675-10 µg, ATGP2675-20 µg, ATGP2675-50 µg, ATGP2675-100 µg, ATGP2675-250 µg, ATGP2675-500 µg, ATGP2675-1 mg, ATGP2675-10, ATGP2675-20, ATGP2675-50, ATGP2675-100, ATGP2675-250, ATGP2675-500, ATGP2675-1

Prabakaran T, Nielsen R., et al. (2012) PLoS One. 2012;7 (6) :e39975.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Immunology

NP_002346

P20645

Human

TEEKTCD LVGEKGKESE KELALVKRLK PLFNKSFEST VGQGSDTYIY IFRVCREAGN HTSGAGLVQI NKSNGKETVV GRLNETHIFN GSNWIMLIYK GGDEYDNHCG KEQRRAVVMI SCNRHTLADN FNPVSEERGK VQDCFYLFEM DSSLACSPEI SH