Recombinant humaan CD107a/LAMP1-eiwit

LAMP1, also known as lysosome-associated membrane glycoprotein 1, is a membrane protein that belongs to the LAMP family. It is expressed in the endosome-lysosome membranes of cells, but is also found on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets. A glycoform of LAMP1 is expressed on the surface of activated macrophages where it promotes T cell co-stimulation and a Th1 biased immune response. Recombinant human LAMP1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Lysosome-associated membrane glycoprotein 1, LAMP1, CD107a, LAMPA, LGP120, CD107 antigen-like family member A

Baculovirus

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

39.4 kDa (363aa)

LAMP1, CD107a, Lysosome-associated membrane glycoprotein 1, LAMP1, CD107a, LAMPA, LGP120, ATGP3694-10 µg, ATGP3694-20 µg, ATGP3694-50 µg, ATGP3694-100 µg, ATGP3694-250 µg, ATGP3694-500 µg, ATGP3694-1 mg, ATGP3694-10, ATGP3694-20, ATGP3694-50, ATGP3694-100, ATGP3694-250, ATGP3694-500, ATGP3694-1

Dange MC., et al, (2015) Mol Cell Biochem. 404:79-86.; ; Okato A., et al, (2016) Int J Oncol. 49:111-122.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Neuroscience

NP_005552

P11279

Human

Ala

ADPAMFMVKN GNGTACIMAN FSAAFSVNYD TKSGPKNMTF DLPSDATVVL NRSSCGKENT SDPSLVIAFG RGHTLTLNFT RNATRYSVQL MSFVYNLSDT HLFPNASSKE IKTVESITDI RADIDKKYRC VSGTQVHMNN VTVTLHDATI QAYLSNSSFS RGETRCEQDR PSPTTAPPAP PSPSPSPVPK SPSVDKYNVS GTNGTCLLAS MGLQLNLTYE RKDNTTVTRL LNINPNKTSA SGSCGAHLVT LELHSEGTTV LLFQFGMNAS SSRFFLQGIQ LNTILPDARD PAFKAANGSL RALQATVGNS YKCNAEEHVR VTKAFSVNIF KVWVQAFKVE GGQFGSVEEC LLDENSMHHH HHH