Recombinant humaan CD157 eiwit

BST1, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, is a glycosylphosphatidyl inositol (GPI) anchored membrane protein that belongs to the CD38 family. It was originally identified as a bone marrow stromal cell molecule. This protein is an ectoenzyme sharing several characteristics with ADP-ribosyl cyclase CD38. Along with CD38, it exhibits both DP-ribosyl cyclase and cyclinc ADP ribose hydrolase activities. It may play a role in rheumatoid arthritis (RA) due to its enhanced expression in RA-derived bone marrow stromal cell lines. Also, it is expressed by cells of the myeloid lineage and could act as a receptor with signal transduction capability. Recombinant human BST1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, BST1, CD157

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 0.1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

30.5 kDa (267aa)

CD157, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, BST1, CD157, ATGP3801-10 µg, ATGP3801-20 µg, ATGP3801-50 µg, ATGP3801-100 µg, ATGP3801-250 µg, ATGP3801-500 µg, ATGP3801-1 mg, ATGP3801-10, ATGP3801-20, ATGP3801-50, ATGP3801-100, ATGP3801-250, ATGP3801-500, ATGP3801-1

Kaisho T., et al, (1994) Proc. Natl. Acad. Sci. U.S.A. 91:5325-5329.; ; Okuyama Y., et al, (1996) Biochem. Biophys. Res. Commun. 228:838-845.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_004325.2

Q10588

Human

Arg33