Recombinant humaan CD163 eiwit

CD163, also known as scavenger receptor cysteine-rich type 1 protein M130 isoform a, is a scavenger receptor for the hemoglobin-haptoglobin complex that is essential in liver, spleen and circulation. This protein is generated by ectodomain shedding of the membrane bound receptor. Also, it is upregulated in a large range of inflammatory diseases including liver cirrhosis, macrophage activation syndrome, HIV infection and sepsis. Recombinant human CD163, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Scavenger receptor cysteine-rich type 1 protein M130 isoform, CD163, M130, MM130, SCARI1

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

109.8 kDa (1015aa)

CD163, Scavenger receptor cysteine-rich type 1 protein M130 isoform, CD163, M130, MM130, SCARI1, ATGP3696-10 µg, ATGP3696-20 µg, ATGP3696-50 µg, ATGP3696-100 µg, ATGP3696-250 µg, ATGP3696-500 µg, ATGP3696-1 mg, ATGP3696-10, ATGP3696-20, ATGP3696-50, ATGP3696-100, ATGP3696-250, ATGP3696-500, ATGP3696-1

Droste A., et al, (1999) Biochem. Biophys. Res. Commun. 256:110-113.; ; Stover CM., et al, (2000) Cytogenet. Cell Genet. 90:246-247.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Immunology

NP_004235

Q86VB7

Human

Ser42