Recombinant humaan CD164-eiwit

CD164, also known as sialomucin core protein 24 isoform 1, is a type I transmembrane O-glycosylated protein that is expressed on activated perivascular and stromal cells in embryonic and tumor neovasculature. It plays a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to the stroma and by negatively regulating CD34+CD38 (lo/-) cell proliferation. This protein also plays an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Recombinant human CD164 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Sialomucin core protein 24 isoform 1, CD164, DFNA66, endolyn, MGC-24, MGC-24v, MUC-24

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

15.6 kDa (148aa)

CD164, Sialomucin core protein 24 isoform 1, CD164, DFNA66, endolyn, MGC-24, MGC-24v, MUC-24, ATGP3708-10 µg, ATGP3708-20 µg, ATGP3708-50 µg, ATGP3708-100 µg, ATGP3708-250 µg, ATGP3708-500 µg, ATGP3708-1 mg, ATGP3708-10, ATGP3708-20, ATGP3708-50, ATGP3708-100, ATGP3708-250, ATGP3708-500, ATGP3708-1

Huang AF., et al, (2013) Mol Cancer. 12:115.; ; Guenova E., et al, (2016) Acta Derm Venereol. 96:464-467.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cancer

NP_006007

Q04900

Human

Ala

ADPDKNTTQH PNVTTLAPIS NVTSAPVTSL PLVTTPAPET CEGRNSCVSC FNVSVVNTTC FWIECKDESY CSHNSTVSDC QVGNTTDFCS VSTATPVPTA NSTAKPTVQP SPSTTSKTVT TSGTTNNTVT PTSQPVRKST FDHHHHHH