Recombinant humaan CD1d-eiwit

CD1D, also known as antigen-presenting glycoprotein CD1d isoform 1, is a transmembrane glycoprotein in the CD1 family of glycolipid antigen-presenting MHC-like molecules. CD1d-presented lipid antigens activate a special class of T cells, known as natural killer T (NKT) cells, through the interaction with the T-cell receptor present on NKT membranes. When activated, NKT cells rapidly produce Th1 and Th2 cytokines, typically represented by interferon-gamma and interleukin 4 production. Recombinant human CD1D protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Antigen-presenting glycoprotein CD1d isoform 1, CD1D, CD1A, R3, R3G1

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

32.9 kDa (290aa)

CD1d, Antigen-presenting glycoprotein CD1d isoform 1, CD1D, CD1A, R3, R3G1, ATGP3678-10 µg, ATGP3678-20 µg, ATGP3678-50 µg, ATGP3678-100 µg, ATGP3678-250 µg, ATGP3678-500 µg, ATGP3678-1 mg, ATGP3678-10, ATGP3678-20, ATGP3678-50, ATGP3678-100, ATGP3678-250, ATGP3678-500, ATGP3678-1

Broxmeyer HE., et al, (2012) Blood. 119:5731-5741.; ; Huh JY., et al, (2017) Diabetes. 66:835-847.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_001757.1

P15813

Human

Glu20