Recombinant humaan CD1D-eiwit met C-terminaal humaan Fc-tag

Expression Host : HEK293 The protein has a predicted molecular mass of 56.54 kDa after removal of the signal peptide. This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.

CD1A; R3; R3G1

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Delivery in 4-6 weeks

Store at -80°C for 12 months (Avoid repeated freezing and thawing)