Recombinant humaan CD200-eiwit

CD200, also known as OX-2 membrane glycoprotein isoform a, is a transmembrane immuno- regulatory protein that belongs to the immunoglobulin superfamily. Its receptor (CD200R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD200. Elevated expression of this protein has been reported to be associated with poor prognosis in a number of human malignancies. In addition, it also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion. Recombinant human CD200 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

OX-2 membrane glycoprotein isoform a, CD200, MOX1, MOX2, MRC, OX-2

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.5 mg/mL (determined by BCA Assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

49.7 kDa (444aa)

CD200, OX-2 membrane glycoprotein isoform a, CD200, MOX1, MOX2, MRC, OX-2, ATGP3557-10 µg, ATGP3557-20 µg, ATGP3557-50 µg, ATGP3557-100 µg, ATGP3557-250 µg, ATGP3557-500 µg, ATGP3557-1 mg, ATGP3557-10, ATGP3557-20, ATGP3557-50, ATGP3557-100, ATGP3557-250, ATGP3557-500, ATGP3557-1

Akkaya M., et al. (2013) PLoS One. 8:e63325.; ; Li L., et al. (2016) Med Sci Monit. 22:1079-1084.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_005935

P41217

Human

Ala

ADPQVQVVTQ DEREQLYTPA SLKCSLQNAQ EALIVTWQKK KAVSPENMVT FSENHGVVIQ PAYKDKINIT QLGLQNSTIT FWNITLEDEG CYMCLFNTFG FGKISGTACL TVYVQPIVSL HYKFSEDHLN ITCSATARPA PMVFWKVPRS GIENSTVTLS HPNGTTSVTS ILHIKDPKNQ VGKEVICQVL HLGTVTDFKQ TVNKGLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH