Recombinant humaan CD21-eiwit

CD21, also known as complement receptor type 2 isoform 2, is an N-glycosylated member of the regulators of complement activation family of proteins. This protein is present on all mature B-cells and some T-cells and follicular dendritic cells and is released by proteolytic shedding from activated B cell. It forms a complex with the B cell receptor-associated CD19 molecule and lowers the threshold for B cell activation. It binds the complement component fragments iC3b, C3D, and C3d. Also, this protein has a function in the complement system through serving as the cellular receptor specific for ligands such as C3 and C4. Recombinant Human CD21, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

CD21, CR2, Cr2, C3DR, CR, CVID7, SLEB9, Complement receptor type 2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

105.2 kDa (959aa)

CD21, ATGP3887-10 µg, ATGP3887-20 µg, ATGP3887-50 µg, ATGP3887-100 µg, ATGP3887-250 µg, ATGP3887-500 µg, ATGP3887-1 mg, ATGP3887-10, ATGP3887-20, ATGP3887-50, ATGP3887-100, ATGP3887-250, ATGP3887-500, ATGP3887-1, ATGP3887-10 µg, ATGP3887-20 µg, ATGP3887-50 µg, ATGP3887-100 µg, ATGP3887-250 µg, ATGP3887-500 µg, ATGP3887-1 mg, ATGP3887-10, ATGP3887-20, ATGP3887-50, ATGP3887-100, ATGP3887-250, ATGP3887-500, ATGP3887-1

Tanner J., et al, (1987) Cell 50:203-213.; ; Carel JC., et al, (1990) J. Biol. Chem. 265:12293.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_001868.2

P20023

Human

Ile21