Recombinant humaan CD229/SLAMF3-eiwit

LY9, as known as T-lymphocyte surface antigen Ly-9 isoform, is a type 1 transmembrane glycoprotein in the SLAM subgroup of the CD2 family. This protein consists of an extracellular domain with two lg-like V-set and two lg-like truncated C2-set domains. It is expressed on T and B cells, thymocytes, and more weakly on NK cells. Homophilic binding between LY9 molecules is mediated by the N-terminal lg-like domain. Also, this protein knockout mice show minimally impaired immune responses, suggesting functional redundancy with other molecules. Recombinant human LY9, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

T-lymphocyte surface antigen Ly-9 isoform, LY9, CD229, hly9, mLY9, SLAMF3, CD229 Cell surface molecule Ly-9, Cell surface molecule Ly9, hly9, LY 9, Ly9, LY9_HUMAN, Lymphocyte antigen 9, mLY9, Signaling lymphocytic activation molecule 3, SLAM family member 3, SLAMF3, T lymphocyte surface antigen Ly9 precursor, T-lymphocyte surface antigen Ly-9

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

45.9 kDa (416aa)

CD229, SLAMF3, T-lymphocyte surface antigen Ly-9 isoform , LY9, CD229, hly9, mLY9, SLAMF3, CD229Cell surface molecule Ly-9, Cell surface molecule Ly9hly9, LY 9, Ly9, LY9_HUMAN, Lymphocyte antigen 9mLY9, Signaling lymphocytic activation molecule 3SLAM family member 3, SLAMF3, T lymphocyte surface antigen Ly9 precursor, T-lymphocyte surface antigen Ly-9, ATGP3400-10 µg, ATGP3400-20 µg, ATGP3400-50 µg, ATGP3400-100 µg, ATGP3400-250 µg, ATGP3400-500 µg, ATGP3400-1 mg, ATGP3400-10, ATGP3400-20, ATGP3400-50, ATGP3400-100, ATGP3400-250, ATGP3400-500, ATGP3400-1

Hagberg N., et al. (2013) J. Immunol. 191:2989-2998.; ; Chatterjee M., et al. (2012) J. Biol. Chem. 287:38168-38177.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_002339

Q9HBG7

Human

Ala

KDSAPTV VSGILGGSVT LPLNISVDTE IENVIWIGPK NALAFARPKE NVTIMVKSYL GRLDITKWSY SLCISNLTLN DAGSYKAQIN QRNFEVTTEE EFTLFVYEQL QEPQVTMKSV KVSENFSCNI TLMCSVKGAE KSVLYSWTPR EPHASESNGG SILTVSRTPC DPDLPYICTA QNPVSQRSSL PVHVGQFCTD PGASRGGTTG ETVVGVLGEP VTLPLALPAC RDTEKVVWLF NTSIISKERE EAATADPLIK SRDPYKNRVW VSSQDCSLKI SQLKIEDAGP YHAYVCSEAS SVTSMTHVTL LIYRRLRKPK ITWSLRHSED GICRISLTCS VEDGGNTVMY TWTPLQKEAV VSQGESHLNV SWRSSENHPN LTCTASNPVS RSSHQFLSEN ICSGPERNTK