Recombinant humaan CD27-eiwit met C-terminaal humaan Fc-tag
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Expression Host : HEK293 The protein has a predicted molecular mass of 45.3 kDa after removal of the signal peptide.The apparent molecular mass of CD27-hFC is approximately 55-70 kDa due to glycosylation. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
CD27, TNFRSF7, S152, T14, Tp55
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Delivery in 1-2 weeks
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Beschrijving
Expression Host : HEK293 The protein has a predicted molecular mass of 45.3 kDa after removal of the signal peptide.The apparent molecular mass of CD27-hFC is a
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