Recombinant humaan CD3 delta/CD3D eiwit

CD3D, also known as T-cell surface glycoprotein CD3 delta chain isoform A, is a single-pass type 1 membrane protein. This protein together with CD3-gamma, CD3-epsilon and CD3-zeta, and the T-cell receptor (TCR) alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. Also, this protein plays an essential role in adaptive immune response and plays an essential role in thymocyte differentiation. Recombinant human CD3D, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

T-cell surface glycoprotein CD3 delta chain isoform A, CD3 delta subunit of T-cell receptor complex, T3D, CD3d antigen, Delta polypeptide, TiT3 complex, CD3d molecule, delta, CD3-TCR complex, CD3-DELTA

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

36.5 kDa (323aa)

CD3D, T-cell surface glycoprotein CD3 delta chain isoform A, CD3D, CD3-DELTA, CD3 delta, MD19, T3D, ATGP3783-10 µg, ATGP3783-20 µg, ATGP3783-50 µg, ATGP3783-100 µg, ATGP3783-250 µg, ATGP3783-500 µg, ATGP3783-1 mg, ATGP3783-10, ATGP3783-20, ATGP3783-50, ATGP3783-100, ATGP3783-250, ATGP3783-500, ATGP3783-1

Hori T., et al, (1991) Int. Immunol. 3:353-357.; ; Phillips JH., et al, (1992) J. Exp. Med. 175:1055-1066.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_000723

P04234

Human

Phe22