Recombinant humaan CD3 gamma/CD3G eiwit

The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. Recombinant human CD3G protein, fused to His-tag at N-terminus, was expressed in E. coli.

T-cell surface glycoprotein CD3 gamma chain, CD3G, CD3-GAMMA, IMD17, T3G, CD3 gamma subunit of T-cell receptor complex, CD3g antigen gamma polypeptide, TiT3 complex, T-cell receptor T3 gamma chain

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

13.1 kDa (117aa)

CD3G, CD3g molecule gamma (CD3-TCR complex), CD3g molecule, gamma (CD3-TCR complex), CD3-GAMMA, T3G, ATGP2000-10 µg, ATGP2000-20 µg, ATGP2000-50 µg, ATGP2000-100 µg, ATGP2000-250 µg, ATGP2000-500 µg, ATGP2000-1 mg, ATGP2000-10, ATGP2000-20, ATGP2000-50, ATGP2000-100, ATGP2000-250, ATGP2000-500, ATGP2000-1

Kjer-Nielsen L., et al. (2004) Proc. Natl. Acad. Sci. u.S.A. 101:7675-7680; ; Tao W.A., et al. (2005) Nat. Methods. 2:591-598;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Immunology

NP_000064

P09693

Human

MGSSHHHHHH SSGLVPRGSH MGSQSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATIS