Recombinant humaan CD3 gamma/CD3G eiwit

CD3G, also known as T-cell surface glycoprotein CD3 gamma chain, is associated on the T cell surface with a complex of protein called CD3. The protein is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal transduction pathways. Defects in this gene are associated with T cell immunodeficiency. Recombinant human CD3G protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

T-cell surface glycoprotein CD3 gamma chain, CD3G, CD3-GAMMA, IMD17, T3G, CD3 gamma subunit of T-cell receptor complex, CD3g antigen gamma polypeptide, TiT3 complex, T-cell receptor T3 gamma chain

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

11.8 kDa (103aa)

CD3G, T-cell surface glycoprotein CD3 gamma chain, CD3G, CD3-GAMMA, IMD17, T3G, ATGP3551-10 µg, ATGP3551-20 µg, ATGP3551-50 µg, ATGP3551-100 µg, ATGP3551-250 µg, ATGP3551-500 µg, ATGP3551-1 mg, ATGP3551-10, ATGP3551-20, ATGP3551-50, ATGP3551-100, ATGP3551-250, ATGP3551-500, ATGP3551-1

Munoz-Ruiz M., et al. (2013) BMC Immunol. 14: 3.; ; Gokturk B., et al. (2014) Scand J Immunol. 80:354-361.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_000064

P09693

Human

Ala

ADPQSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATISHHH HHH