Recombinant humaan CD301/CLEC10A-eiwit

CLEC10A, also known as C-type lectin domain family 10 member A isoform 2, is a C-type lectin superfamily member 14. It is expressed on immature myeloid dendritic cells and alternatively activated macrophages. This protein roles in regulating adaptive and innate immune responses. Also, it binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine, linked to serine or threonine. Recombinant human CLEC10A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

C-type lectin domain family 10 member A isoform 2, CLEC10A, CD301, CLECSF13, CLECSF14, HML, HML2, MGL, Macrophage lectin 2

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

27.3 kDa (241aa)

CLEC10A, CD301, C-type lectin domain family 10 member A isoform 2, CLEC10A, CD301, CLECSF13, CLECSF14, HML, HML2, MGL, ATGP3591-10 µg, ATGP3591-20 µg, ATGP3591-50 µg, ATGP3591-100 µg, ATGP3591-250 µg, ATGP3591-500 µg, ATGP3591-1 mg, ATGP3591-10, ATGP3591-20, ATGP3591-50, ATGP3591-100, ATGP3591-250, ATGP3591-500, ATGP3591-1

Lenos K., et al, (2015) Oncotarget 6:26278-26290.; ; Zizzari IG., et al, (2015) PLoS ONE 10:E0132617.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Immunology

NP_006335

Q8IUN9

Human

Ala

QNSKFQR DLVTLRTDFS NFTSNTVAEI QALTSQGSSL EETIASLKAE VEGFKQERQA VHSEMLLRVQ QLVQDLKKLT CQVATLNNNG EEASTEGTCC PVNWVEHQDS CYWFSHSGMS WAEAEKYCQL KNAHLVVINS REEQNFVQKY LGSAYTWMGL SDPEGAWKWV DGTDYATGFQ NWKPGQPDDW QGHGLGGGED CAHFHPDGRW NDDVCQRPYH WVCEAGLGQT SQES