Recombinant humaan CD316/IGSF8 eiwit

IGSF8, also known as Immunoglobulin superfamily member 8, is a member of the immunoglobulin protein superfamily. It interact with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. Also, this protein may function as a tumor suppressor by inhibiting the proliferation of certain cancers. Recombinant human IGSF8 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Immunoglobulin superfamily member 8, IGSF8, CD316, CD81P3, EWI-2, EWI2, KCT-4, LIR-D1, PGRL, CD81 partner 3, Glu-Trp-Ile EWI motif-containing protein 2, Keratinocytes-associated transmembrane protein 4, Prostaglandin regulatory-like protein

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

59.6 kDa (561aa)

IGSF8, Immunoglobulin superfamily member 8, IGSF8, CD316, CD81P3, EWI-2, EWI2, KCT-4, LIR-D1, PGRL, ATGP3629-10 µg, ATGP3629-20 µg, ATGP3629-50 µg, ATGP3629-100 µg, ATGP3629-250 µg, ATGP3629-500 µg, ATGP3629-1 mg, ATGP3629-10, ATGP3629-20, ATGP3629-50, ATGP3629-100, ATGP3629-250, ATGP3629-500, ATGP3629-1

Kolesnikova TV., et al, (2004) Blood. 103:3013-3019.; ; Wang HX., et al, (2015) Cell Res. 25:370-385.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol

Virus

NP_443100

Q969P0

Human

Ala

ADLREVLVPE GPLYRVAGTA VSISCNVTGY EGPAQQNFEW FLYRPEAPDT ALGIVSTKDT QFSYAVFKSR VVAGEVQVQR LQGDAVVLKI ARLQAQDAGI YECHTPSTDT RYLGSYSGKV ELRVLPDVLQ VSAAPPGPRG RQAPTSPPRM TVHEGQELAL GCLARTSTQK HTHLAVSFGR SVPEAPVGRS TLQEVVGIRS DLAVEAGAPY AERLAAGELR LGKEGTDRYR MVVGGAQAGD AGTYHCTAAE WIQDPDGSWA QIAEKRAVLA HVDVQTLSSQ LAVTVGPGER RIGPGEPLEL LCNVSGALPP AGRHAAYSVG WEMAPAGAPG PGRLVAQLDT EGVGSLGPGY EGRHIAMEKV ASRTYRLRLE AARPGDAGTY RCLAKAYVRG SGTRLREAAS ARSRPLPVHV REEGVVLEAV AWLAGGTVYR GETASLLCNI SVRGGPPGLR LAASWWVERP EDGELSSVPA QLVGGVGQDG VAELGVRPGG GPVSVELVGP RSHRLRLHSL GPEDEGVYHC APSAWVQHAD YSWYQAGSAR SGPVTVYPYM HALDTHHHHH H