Recombinant humaan CD32a/FCGR2A-eiwit

Low affinity immunoglobulin gamma Fc region receptor II-a, also known as FCGR2A, is a member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. This protein is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Recombinant human FCGR2A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Low affinity immunoglobulin gamma Fc region receptor II-a, IgG Fc receptor II-a, CDw32, Fc gamma receptor Iia, Fc-gamma RII-a, Fc-gamma-RIIa, FcRII-a, CD32, FCGR2A, CD32A, FCG2, FCGR2A1, IGFR2

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

23.0 kDa (208aa) confirmed by MALDI-TOF

Fc g RIIA, CD32a, Low affinity immunoglobulin gamma Fc region receptor II-a, CD32, CD32A, CDw32, FcGR, IGFR2, MGC23887, MGC30032, ATGP1936-10 µg, ATGP1936-20 µg, ATGP1936-50 µg, ATGP1936-100 µg, ATGP1936-250 µg, ATGP1936-500 µg, ATGP1936-1 mg, ATGP1936-10, ATGP1936-20, ATGP1936-50, ATGP1936-100, ATGP1936-250, ATGP1936-500, ATGP1936-1

Lu J., et al. (2008) Nature. 456:989-992; ; Rikova K., et al. (2007) Cell. 131:1190-1203

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 50% glycerol, 1mM DTT

Immunology

AAH19931.1

P12318

Human

QAAPP KAVLKLEPPW INVLQEDSVT LTCQGARSPE SDSIQWFHNG NLIPTHTQPS YRFKANNNDS GEYTCQTGQT SLSDPVHLTV LSEWLVLQTP HLEFQEGETI MLRCHSWKDK PLVKVTFFQN GKSQKFSRLD PTFSIPQANH SHSGDYHCTG NIGYTLFSSK PVTITVQVPS MGSSSPMG