Recombinant humaan CD34-eiwit

CD34, also known as hematopoietic progenitor cell antigen CD34 isoform b, is a member of a family of single-pass transmembrane sialomucin proteins. It is adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. This protein could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Recombinant human CD34, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Hematopoietic progenitor cell antigen CD34 isoform b, CD34

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by BCA assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

28.6 kDa (268aa)

CD34, Hematopoietic progenitor cell antigen CD34 isoform b, CD34, ATGP3447-10 µg, ATGP3447-20 µg, ATGP3447-50 µg, ATGP3447-100 µg, ATGP3447-250 µg, ATGP3447-500 µg, ATGP3447-1 mg, ATGP3447-10, ATGP3447-20, ATGP3447-50, ATGP3447-100, ATGP3447-250, ATGP3447-500, ATGP3447-1

Nielsen JS., et al. (2009) Microcirculation. 16:487-496.; ; Mastrandrea F., et al. (2008) Eur Ann Allergy Clin Immunol. 40:90-103.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Neuroscience

NP_001764.1

P28906

Human

Ala

SLDNNGT ATPELPTQGT FSNVSTNVSY QETTTPSTLG STSLHPVSQH GNEATTNITE TTVKFTSTSV ITSVYGNTNS SVQSQTSVIS TVFTTPANVS TPETTLKPSL SPGNVSDLST TSTSLATSPT KPYTSSSPIL SDIKAEIKCS GIREVKLTQG ICLEQNKTSS CAEFKKDRGE GLARVLCGEE QADADAGAQV CSLLLAQSEV RPQCLLLVLA NRTEISSKLQ LMKKHQSDLK KLGILDFTEQ DVASHQSYSQ KT