Recombinant humaan CD38-eiwit

CD38, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, is a surface molecule which has been attributed the function of a signaling channel leading to cellular activation and proliferation, an ectoenzyme with multiple function as well as an inducer of Ca2+ mobilization from cytoplasmic stores. It also functions as a plasma membrane signaling receptor in leukocytes. On B cells, It acts as a coreceptor and modulates B cell receptor (BCR) signals. Recombinant human CD38, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, CD38, ADPRC 1, ADPRC1

Baculovirus

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

31.2 kDa (269aa)

CD38, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, CD38, ADPRC 1, ADPRC1, ATGP3339-10 µg, ATGP3339-20 µg, ATGP3339-50 µg, ATGP3339-100 µg, ATGP3339-250 µg, ATGP3339-500 µg, ATGP3339-1 mg, ATGP3339-10, ATGP3339-20, ATGP3339-50, ATGP3339-100, ATGP3339-250, ATGP3339-500, ATGP3339-1

Funaro A., et al. (1997) Tissue Antigens. 49:7-15.; ; Lischke., et al. (2013) Infect Immun. 81:4091-4099.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 50 mM MES buffer (pH 5.0) containing 100 mM NaCl, 10% glycerol

Immunology

NP_001766

P28907

Human

Ala

ADPEFVPRWR QQWSGPGTTK RFPETVLARC VKYTEIHPEM RHVDCQSVWD AFKGAFISKH PCNITEEDYQ PLMKLGTQTV PCNKILLWSR IKDLAHQFTQ VQRDMFTLED TLLGYLADDL TWCGEFNTSK INYQSCPDWR KDCSNNPVSV FWKTVSRRFA EAACDVVHVM LNGSRSKIFD KNSTFGSVEV HNLQPEKVQT LEAWVIHGGR EDSRDLCQDP TIKELESIIS KRNIQFSCKN IYRPDKFLQC VKNPEDSSCT SEIHHHHHH