Recombinant humaan CD4-eiwit

CD4, also known as T-cell surface glycoprotein CD4, is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It interacts directly with MHC class II molecules on the surface of the antigen presenting cell via its extracellular domain. It is a co-receptor that assists the T cell receptor (TCR) to activate its T cell following an interaction with an antigen presenting cell. Recombinant human CD4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

T-cell surface glycoprotein CD4, CD4, CD4mut

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

42.1 kDa (377aa)

CD4, ATGP3374-10 µg, ATGP3374-20 µg, ATGP3374-50 µg, ATGP3374-100 µg, ATGP3374-250 µg, ATGP3374-500 µg, ATGP3374-1 mg, ATGP3374-10, ATGP3374-20, ATGP3374-50, ATGP3374-100, ATGP3374-250, ATGP3374-500, ATGP3374-1

Singh SK., et al. (2012) FEBS J. 279:3705-3714.; ; Farrar WL., et al. (1988) Crit Rev Immunol. 8:315-339.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_000607

P01730

Human

Lys26